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Supply Dostinex Solid Cabergoline 81409-90-7 to Treat Hormone Imbalance

Basic Info

Model No.:  81409-90-7

Product Description

Model NO.: 81409-90-7 Customized: Non-Customized Suitable for: Adult Purity: >99% Molecular Formula: C26h37n5o2 Trademark: Saichuang Specification: qualified HS Code: 4301300000 Powder: Yes Certification: ISO 9001 State: Solid CAS: 81409-90-7 Molecular Weight: 451.6 Transport Package: Discreet Origin: China Effective Cabergoline CAS 81409-90-7 Oral Tablet Powder Parkinson's Disease

 
 
 

Quick detail:
CAS No: 81409-90-7
M.Wt: 451.6
Formula: C26H37N5O2
Solubility: Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity: 99 %min
Storage: Store at +4°C
Appearance: white powder 
 
Description:
Cabergoline is used to treat different types of medical problems that occur when too much of the 
hormone prolactin is produced. It can be used to treat certain menstrual problems, fertility problems 
in men and women, and pituitary prolactinomas (tumors of the pituitary gland).It works by stopping
the brain from making and releasing the prolactin hormone from the pituitary 
gland.
 
Cabergoline use is usually stopped when prolactin levels are normal for 6 months. It may be given 
again if symptoms of too much prolactin occur again.
This medicine is available only with your doctor's prescription.
This product is available in the following dosage forms: Tablet
 
Originally introduced by the anti-aging community to the bodybuilding world, this dopamine receptor agonist has the chemical name of 1-[(6-allylergolin-8?-yl)-carbonyl]-1-[3-(dimethylamino) propyl]-3-ethylurea and tablets of this drug include 0.5 mg of cabergoline and the list of inactive ingredients includes leucine, USP, lactose, and NF.
Dostinex-Cabergoline has a chemical name of 1-[(6-allylergolin-8?-yl)-carbonyl]-1-[3-(dimethylamino) propyl]-3-ethylurea. The empirical formula for this drug is C26H37N5O2 and its molecular weight is 451.62.
 
 
Application:
The biggest reason why Cabergoline is admired by amateur and professional athletes is because it
helps them reduce or eliminate the risks associated with excess prolactin that is common with use of harsh and aromatizable steroids like Trenbolone and Deca Durabolin. Furthermore, this drug is also useful for treating sexual dysfunction caused by excess prolactin besides gaining an erection between orgasms and reducing recovery time after intense workouts or weight training and strength training exercises. In addition to these advantages, the use of Dostinex is equally beneficial to combat
estrogenic side effects such as oily skin, acne, gynecomastia, and bloating and treating health complications like galactorrhea and sexual dysfunction. It is also routinely indicated to patients with Parkinson's disease as it has the potential to work on information pathways and nervous system of
the body. Dostinex is also admired for its ability to make athletes feel 'full' that helps in minimizing food cravings without dieting discomfort.
 
Cabergoline is an ergot medication and works by blocking the release of prolactin from the pituitary gland.Dostinex is used to treat Parkinson's disease, to prevent women producing milk when they
want to stop breast feeding(hyperprolactinemia), Cabergoline can lower prolactin levels in patients
with a pituitary tumor. Cabergoline is also sometimes used to help men with sexual dysfunction.
 
1. hyperprolactinemia
2. adjunctive therapy of prolactin-producing pituitary gland tumors (prolactinomas);
3. monotherapy of Parkinson's disease in the early phase;
4. combination therapy, together with levodopa and a decarboxylase inhibitor such as carbidopa, in progressive-phase Parkinson's disease;
5. in some countries also: ablactation and dysfunctions associated with hyperprolactinemia (amenorrhea, oligomenorrhea, anovulation, nonpuerperal mastitis and galactorrhea);
6. treatment of uterine fibroids.
7. adjunctive therapy of acromegaly, cabergoline has low efficacy in suppressing levels and is highly efficient in suppressing hyperprolactinemia that is present in 20-30% of acromegaly cases;
8.and prolactin are similar structurally and have similar effects in many target tissues, therefore targeting prolactin may help symptoms when hormone secretion can not be sufficiently controlled by other methods;
9. Cushing's disease - cabergoline may be used to lower ACTH levels and cause regression of ACTH producing pituitary adenomas;
10. other pituitary adenomas - cabergoline has demonstrated certain efficacy in controlling or reducing other kinds of pituitary adenomas, as well as silent or non-functional adenomas.

 How to use cabergoline:
Use cabergoline as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Take cabergoline by mouth with or without food.
It may be helpful to mark on a calendar which days you are supposed to take cabergoline.
If you miss a dose of cabergoline, contact your doctor right away.
Ask your health care provider any questions you may have about how to use cabergoline.
 
Dosage
Parkinson's disease: Monotherapy: Initial dose should be 0.5 mg daily. The usual maintenance dose is 2 to 4 mg daily. Combination therapy: Usually 2 to 6 mg daily.
Tumors of the pituitary gland and other hyperprolactinemic conditions: Initially 0.5 mg per week, slowly titrated to 4.5 mg per week, if necessary.
Ablactation: According to specific treatment scheme.
 
COA

Product Name:
Cabergoline Batch No 201505001
Analysis Date 2015. 06. 01 MFG Date 2015. 05. 07
Quantity 298g CAS 81409-90-7
Standard: EP6.0/ USP38 packing -
 
ITEM       LIMIT RESULT
   Description White or almost white crystarlline powder Conforn
 Identify 1.  IR complies
2.  X-Ray complies
3.  HPLC complies
Conforn
Conforn
Conforn
Water           No more than 0.5% 0.2%
Reiated substances 1.Allylamide (USP,rel,D) no more than 0.10%
2. Allyl DHLA(USP,rel,D) no more than 0.15%;
3.Cabergoline oxide no more than 0.10% ;
4.Other impurities individually no more than 0.10% ;
5.Total no more than 0.50% ;
0.02%
Less than 0.02%
Less than 0.02%
Less than 0.02%
 
0.05%
Assay(HPLC) 98.0-102.0% 100.5%
Opdical rotation -83.0--  -77.0 -78
Residual Solvents  
2.Acetone no more than200ppm;
3.Tert-butylmethylether no more than 200ppm;
4.Xylene no more than 1500ppm;
5.HEptane no more than 1000ppm;
Less than30ppm
Less than20ppm
Less than10ppm
110ppm
Less than30ppm
Residue on ignition NO more than0.10 % 0.02%
Heavy metals NO more than 20ppm 2ppm
Partcle size 90%af particles no mone than 80μm Conform
Bulk Density 0.2~0.35g/em 0.33g/em
 Conclusion Conforn with  EP6.0/ USP38
Supervisor Yang DeXin Analyst ChenJiaoJiao
Starage terms:Preserve in tight,light resistant containers at atemperature    from+2ºCto+8ºC
 
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