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Whitening Skin Use Medicine Monobenzone for Vitiligo

Basic Info

Model No.:  NH932d520

Product Description

Model NO.: NH932d520 Usage Mode: For external use State: Solid Type: Biological Products Name: Monobenzone Cream(for Vitiligo) MOQ: 1 Box Quality Standard: GMP/Who GMP/Euro GMP Delivery Time: 7 Days Trademark: GUYENNE Specification: GMP/WHO GMP/EURO GMP HS Code: 29095090 Application: Internal Medicine Suitable for: Elderly, Children, Adult Shape: Powder Pharmaceutical Technology: Chemical Synthesis Brand&Origin: Guyenne, France Sample: Acceptable Port: Guangzhou Shelf Life: 36 Months Transport Package: 20g/Tube/Box, 27g/Tube/Box Origin: France MONOBENZONE CREAM


DESCRIPTION

Product Name:

Monobenzone 

Appearance :

White crystline powder

CAS:

103-16-2 

Molecular formula:

C20H20O3 

Molecular weight :

308.371 

Supplier name:          

KINGSCI

Synonyms:

(Benzyloxy)phenol; p-Hydroxyphenyl benzyl ether; 4-(Phenylmethoxy)phenol;
 Agerite alba; Benoquin; Benzoquin; Benzyl hydroquinone; Depigman;
 Hydroquinone benzyl ether; Monobenzone; Monobenzyl hydroquinone; PBP;
 Pigmex; 4-benzyloxy phenol (Monobenzone); 4-benzyloxy phenol; 4-(benzyloxy)phenol; 4-Benzyloxyphenol; PHENOL,4-(PHENYLMETHOXY)- 

Specification

99.5%

 
(1)Monobenzone is the monobenzyl ether of hydroquinone. Monobenzone occurs as a white, almost tasteless crystalline powder, soluble in alcohol and practically insoluble in water.
 
(2)Monobenzone is a compound used as a topical drug for medical depigmentation. The topical application of monobenzone in animals decreases the excretion of melanin from melanocytes. The same action is thought to be responsible for the depigmenting effect of the drug in humans. Monobenzone may cause destruction of melanocytes thus, bringing about permanent dipigmentation in vitiligo patients.
 
(3)Monobenzone is the monobenzyl ether of hydroquinone. Monobenzone powder can be compounded to make a depigmenting cream.  It is used to whiten patchy skin and create and even skin tone that is pale and smooth.
 
(4)Monobenzone USP, is a strong depigmentation agent, used to treat the patients suffering from vitiligo.
 (5)Monobenzone 20% ointment is used specifically for vitiligo.

FUNCTION
1.Monobenzone is a compound used as a topical drug for medical depigmentation.
2.The topical application of monobenzone in animals decreases the excretion of melanin from melanocytes.
3.The same action is thought to be responsible for the depigmenting effect of the drug in humans.
4.Monobenzone may cause destruction of melanocytes and permanent depigmentation.
5.The histology of the skin after depigmentation with topical monobenzone is the same as that seen in vitiligo.
6.The epidermis is normal except for the absence of identifiable melanocytes.
 
 APPLICATION
Monobenzone is used to treat the loss of skin color (vitiligo). It works by permanently removing color from normal skin located around skin with vitiligo. 
Do not use this medication for other skin color conditions (e.g., freckling, age spots, etc.)
 
Production Procedure:
 
Raw Materials----Degreasing and Decalcification-----Enzymolysis----Decolorizing and Deflavour----- Premilinary Millipore Filtration----Refined Filtration---- Concentration------Spray Drying------Prilling-------Package in GMP workshop
 
SPECIFICATION
 

ANALYSIS

SPECIFICATION

RUSULT

Assay (HPLC)

Min 99.5%

99.821%

Characters/appearance

Off White powder

Complies

Melting point

117-122 

Complies

Water 

0.05% Max

Complies

Package & Storage

Store in sealed containers at cool & dry place. Protect from light, moisture and pest infestation.

Shelf Life 

2 years if sealed and avoid direct sun light.

Conclusion

Conforming to standards of European pharmacopoeia 4

  

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Product Categories : Biologicals & Vaccines