Effective Drug Anti Ulcer Esomeprazole for Injection 40mg
Model No.: DAWA4672
1. Product name: Esomeprazole sodium for injection
2. Specification: 40mg
3. Package: 1vial+1amp/box
4. Shelf Life: 36months
5. ACTD format or CTD format regiter dossiers are available.
|Name||Esomeprazole sodium for injection|
Esomeprazole is a proton pump inhibitor which reduces stomach acid secretion through inhibition of the H+/K+ATPase in the parietal cells of the stomach.By inhibiting the functioning of this transporter, the drug prevents formation of stomach acid.It is used in the treatment of dyspepsia, peptic ulcer disease, gastroesophageal reflux disease, andZollinger-Ellison syndrome.Esomeprazole is the S-enantiomer of omeprazole As well, Nexium (esomeprazole magnesium) is currently sold over the counter through the US (in the lower, 20 mg dose)
The primary uses of esomeprazole are gastroesophageal reflux disease, treatment and maintenance of erosive esophagitis, treatment of duodenal ulcers caused by H.Pylori, prevention of gastric ulcers in those on chronic NSAID therapy, and treatment of gastrointestinal ulcers associated with Crohn's disease.
Gastroesophageal reflux disease
Gastroesophageal reflux disease (GERD) is a condition in which the digestive acid in the stomach comes in contact with the esophagus.The irritation caused by this disorder is known as heartburn.Long-term contact between gastric acids and the esophagus can cause permanent damage to the esophagus.Esomeprazole reduces the production of digestive acids, thus minimizing their effect on the esophagus.Duodenal ulcerEsomeprazole is combined with the antibiotics clarithromycin and amoxicillin (or metronidazole instead of amoxicillin in penicillin-hypersensitive patients) in a 10 day eradication triple therapy for Helicobacter pylori.Infection by H.Pylori is a causative factor in the majority of peptic and duodenal ulcers.
A 2006 meta analysis concluded that compared to other proton pump inhibitors, esomeprazole confers a statistically significant but clinically modest overall benefit in esophageal healing and symptom relief.When broken down by disease severity, the benefit of esomeprazole relative to other proton pump inhibitors was negligible in patients with mild disease but appeared more substantial in those with severe disease .A second meta analysis also found statistically significant increases in erosive esophageal healing (>95% healing rate) when compared to standardized doses in broadly selected patient populations.
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1. Keep it out of the reach of Children.
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Product Categories : Medical Antibiotics